Rosetta: Article “Deciphering Protein Structures”

Via the NCSA:

The NCSA wrote a very easy to understand, yet quite complete article with explanations about David Baker’s Rosetta project, an theoretical approach to deduct a protein’s structure using computer-simulations.

Things I learned from this article:

1. The code does not start with a “flat” protein-molecule, starting to wiggle it around, but with a “homologous known protein structure” as a starting point. I don’t understand if that’s good or bad, but it limits the permutations to be checked.
2. David created a portal known as Robetta, where other biologists can submit their models to be crunched.
3. The Rosetta-project (not to be confused with Rosetta@home) uses a lot of CPU-hours on NCSA’s clusters and supercomputers (Tungsten Linux Cluster, NCSA Condor Flock, and now possibly TeraGrid resources)

However, quite a nice read, go and grab it while it’s hot!

Tech Tags: BOINC distributed computing Rosetta@home Science

RALPH@home: Alpha test project for Rosetta@home

Via rosetta@home’s Number Crunching forum:

RALPH@home is the official alpha test project for Rosetta@home. New application versions, work units, and updates in general will be tested here before being used for production. The goal for RALPH@home is to improve Rosetta@home.

So if you got any spare CPU-cycles and want to help improving cutting-edge rosetta@home applications, go and sign up!

Tech Tags: rosett@home boinc ralph@home distributed compunting

Rosetta@home: Return your CASP7-results asap

Today, on Monday the 7th, the CASP7-contest is over and the Rosetta@home-team needs to submit their results, as user Feet1st reminds us; so, if you’re a Rosetta@home-cruncher, return your result immediately through marking the rosetta@home application and pressing the “Update”-button in your BOINC-manager application:

Also, if you followed David Baker’s request for more more power, keep in mind that CASP7 will be partly re-evaluated and that further crunching helps science, although CASP7 is over.

Please keep also in mind that Rosetta@home got a 10-mio.-USD grant from the Melinda and Bill Gates foundation for searching a vaccine against the HI-virus. We don’t know yet when those new WUs will be issued, stay tuned for further updates.

Thanks you for crunching for Rosetta@home.

Tags:
rosetta@home, boinc, science, distributed computing, casp